bilateral and stn leads boston scientific vercise cartesiatm directional leads  (Boston Scientific Corporation)

Journal: Annals of Neurology

Article Title: Directional Subthalamic Deep Brain Stimulation Better Improves Gait and Balance Disorders in Parkinson's Disease Patients: A Randomized Controlled Study

doi: 10.1002/ana.27099

Figure Lengend Snippet: Leads locations and volume of tissue activated (VTAs) for ring‐mode, directional central and posterior subthalamic deep brain stimulation (STN‐DBS). (A–C) Coronal, axial, sagittal, and 3 dimensional (3D) posterior views of the VTAs of the 10 Parkinson's disease (PD) patients with central (C, green ) and posterior (D, purple ) STN‐directional DBS (dDBS), and ring‐mode STN‐DBS (E, orange ), for the right and left electrodes. (D) The graph reports the VTAs included in (IN) and outside (OUT) the STN, and the total volumes (SUM), for the central ( green ) and posterior ( purple ) STN‐dDBS, and ring‐mode STN‐DBS ( orange ), for the right (R) and left (L) sides. (E) Individual electrode positions illustrated in a posterior 3D view (Montreal Neurological Institute [MNI] space). The central STN target is shown in color for the STN of each hemisphere. The different subregions of the STN are represented in light green (posterior‐motor), pink (central‐associative), and yellow (anterior‐limbic). (F) Posterior 3D view of the location of the barycenter of each VTA with central ( green ) and posterior ( purple ) STN‐dDBS, and ring‐mode STN‐DBS ( orange ), within the 3D atlas of the basal ganglia in MNI space. Each sphere represents 1 barycenter of 1 individual patient and for 1 side. (G) The graphs report the anteroposterior (Y_axis) and depth (Z_Axis) coordinates of the barycenter of each individual VTAs for ring‐mode (RING) STN‐DBS, and central (CENT), and posterior (POST) STN‐dDBS. *p < 0.05. [Color figure can be viewed at www.annalsofneurology.org ]

Article Snippet: The 2 segmented electrodes (Boston Scientific Neuromodulation Vercise system, Marlborough, MA) were implanted the same day, as previously reported, with direct targeting of the STN using 3 dimensional (3D) T2 fluid attenuated inversion recovery weighted images on preoperative 3 T MRI, and an additional indirect targeting using the basal ganglia atlas for patients operated at the Salpêtrière hospital., The electrodes were connected to the programmable pulse generator (Boston Scientific Neuromodulation Vercise system) and a post‐operative computed tomography (CT)‐scan was performed to confirm the absence of early surgical complications and localization of the leads.

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